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Autologous serum
what it is

Eyedrops produced from one's blood.


This is not a very common dry eye treatment but in clinical studies has shown promising benefits for some patients. Preparation methods vary, which will presumably also play a role in how well they work. For patients who have failed conventional dry eye treatments, autologous serum may be an option to explore.


DRY EYE TALK: Read about patients' experiences with autologous serum in our community forums.

SIFI (Italian manufacturer) overview of autologous serum eye drops

NHS (UK national health system) overview of autologous serum eye drop treatment


ABSTRACT: Combination of transepithelial phototherapeutic keratectomy and autologous serum eyedrops for treatment of recurrent corneal erosions. M P Holzer MD, G U Auffarth MD, H Specht PhD, F E Kruse MD, Jour Cat Refract Surg 2005;31:1603-1606.

ABSTRACT: Comparison of autologous serum eye drops with conventional therapy in a randomised controlled crossover trial for ocular surface disease. B A Noble, R S K Loh, S MacLennan, K Pesudovs, A Reynolds, L R Bridges, J Burr, O Stewart and S Quereshi, British Journal of Ophthalmology 2004;88:647-652

ABSTRACT: Autologous serum eye drops for ocular surface disorders. G Geerling, S MacLennan and D Hartwig. British Journal of Ophthalmology 2004;88:1467-1474.

ABSTRACT: Autologous serum eye drops for the treatment of severe dry eye in patients with chronic graft-versus-host disease. Ogawa Y, Okamoto S, Mori T, Yamada M, Mashima Y, Watanabe R, Kuwana M, Tsubota K, Ikeda Y, Oguchi Y. Bone Marrow Transplant. 2003 Apr;31(7):579-83.

ABSTRACT: Autologous serum eyedrops for dry eyes and epithelial defects: clinical and in vitro toxicity studies. Alexander C Poon, Gerd Geerling, John K G Darta, Graham E Fraenkel, Julie T Daniels. Br J Ophthalmol 2001;85:1188-1197 (October)

ABSTRACT: Treatment of dry eye by autologous serum application in Sjögren's syndrome. Tsubota K, Goto E, Fujita H, Ono M, Inoue H, Saito I, Shimmura S. Br J Ophthalmol 1999; 83(4):384-5.

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